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Range of Services

      A) Invitro Assays to screen putative drug candidates
   
Radio (receptor) Binding Assays: have validated assays for 5HT6 & CBI assays as targets. The other receptors like VR1, VR2, CB2, 5HT2A, 2C,3,5,7 etc can be delivered within 3-4 months from the date of conformation.
 
 
   
Supply of validated receptor membrane preparation. Each lot of membrane preparations would be supplied along with validated data, which includes B max, Kd & Ki values.
 
   
Permeability Assays: Validated Caco2 & MDCK cell lines.
   
Mutagenicity Assays: AMES test; karyotyping and chromosomal analysis
   
Cytotoxicity Assays: Validated MTT Assays.
   
Functional Assays like Cyp P 450 etc
   
Bio Assays : Develop & Validate Bio Assays as per the compendia requirements.
   
Specific / Exclusive Assays : We can develop any specific assays, to be used, exclusively for screening your compounds.
 
   
B) Batch Release Assays for Biotherapeutics
Residual DNA
   
Residual Protein
   
C) Bio Similars
Cloning of genes of therapeutic value, in various expression systems: E. coli,Yeast or Mammalian host.
   
Process optimization and scale up of heterologous protein expression: E. coli, Yeast, Mammalian cells.
   
Downstream processing.
   
Protein purification and characterization of the protein.
   
D) Biotransformation : For API`s
 
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